No. You can not. Asterisk has to be notified when using realtime.
Previously an attempt was made to have it automatically be done, which resulted in a 1000% performance penalty for non-realtime usage that was not acceptable. A compromise was made and this was it.
Thanks now it’s working with “pjsip reload qualify endpoints”
But now the question is:
I’m creating the endpoints in the database from a web application
What is the best way to trigger the reload command from an external web application?